| #6 Aquilla is favored over #13 Union Hill by 16 | Matchup |
| #10 Benjamin is an underdog to #3 Jayton by 27 | Matchup |
| #29 Crowley Nazarene Christian is an underdog to #28 Fort Worth Covenant Classical by 2 | Matchup |
| #1 Gordon is favored over #7 May by 39 | Matchup |
| #26 Houston Emery-Weiner is favored over #27 Pasadena First Baptist by 1 | Matchup |
| #44 Marble Falls Faith is an underdog to #19 Huntsville Alpha Omega by 30 | Matchup |
| #18 Miami is an underdog to #4 Klondike by 27 | Matchup |
| #5 Robert Lee is an underdog to #2 Water Valley by 23 | Matchup |
| #57 San Marcos Hill Country Christian is an underdog to #54 Lake Jackson Brazosport Christian by 2 | Matchup |
| #12 Strawn is favored over #47 Three Way by 39 | Matchup |
| #34 Waco Valor Prep is favored over #76 Azle Christian by 37 | Matchup |
| #41 Waco Vanguard College Prep is favored over #72 Plano Coram Deo by 19 | Matchup |
| #9 Whiteface is favored over #11 Rankin by 3 | Matchup |
| #113 Lantana Harvest Christian is favored over #115 Lubbock Titans by 4 | Matchup |
| #23 Oglesby is an underdog to #8 Richland Springs by 15 | Matchup |
| #109 Stephenville Faith is favored over #121 Georgetown Grace Academy by 9 | Matchup |
| #14 Texas Wind is favored over #17 Brazos Valley Christian (BVCHEA) by 2 | Matchup |